Application of 3D printing individualized guide plates in percutaneous needle biopsy of acetabular tumors

Wen Wu; Siyu Liu; Lei Wang; Bing Wu; Lulu Zhao; Wenbo Jiang; Kerong Dai; Yongqiang Hao; Lingjie Fu; Songtao Ai

doi:10.3389/fgene.2022.955643

Application of 3D printing individualized guide plates in percutaneous needle biopsy of acetabular tumors

Front Genet. 2022 Jul 22:13:955643. doi: 10.3389/fgene.2022.955643. eCollection 2022.

Authors

Wen Wu¹, Siyu Liu², Lei Wang¹, Bing Wu², Lulu Zhao², Wenbo Jiang³, Kerong Dai¹, Yongqiang Hao¹, Lingjie Fu¹, Songtao Ai²

Affiliations

¹ Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Orthopaedic Implants, Shanghai, China.
² Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
³ Engineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education, Shanghai, China.

Abstract

Objective: The objective of the study was to investigate the effectiveness of applying the individualized guide plate which is based on digital image processing and 3D printing technology to percutaneous needle biopsy of periacetabular tumor. Methods: From July 2017 to August 2019, 11 patients (5 males and 6 females, aged 13-70 years, mean 42.3 years) with acetabular tumors diagnosed by needle biopsy in our hospital were enrolled in this retrospective study. Preoperative CT and MRI enhancement examination were performed routinely, and the DICOM data were collected and imported into Medraw Print software. According to the specific anatomical morphology of acetabula, this study adopted the reverse calculation and direct design to print the individualized puncture guide plate using 3D printing technology. The puncture point and sampling approaches were determined by the guide plate morphology and the "double guide-hole and slideable groove" design. First, we evaluated the fitness of the 3D guide plate to the local anatomical structure, its assisted-puncture accuracy was estimated by imaging examinations, and postoperative complications were recorded. The accuracy of the needle biopsy pathological result was estimated with reference to that of the tumor resection. Results: Our results showed that the 3D printing individualized guide plate matched the patients' pelvic skin well, the puncture approach was consistent with the preoperative design, and no significant anatomical injuries including vascular and neural complications occurred after surgery. Nine patients' (90%) biopsy results were consistent with their postoperative pathological results, and one patient gave up the tumor resection. Conclusion: Based on digital image processing and 3D printing technology, the individualized guide plate can be used to guide the needle biopsy of acetabular tumors which makes the operation simpler and more precise.

Keywords: 3D printing technology; acetabular tumors; image registration, and fusion; individualized guide plate; needle biopsy.