Intra- and post-operative risk of retinal breaks during vitrectomy for macular hole and vitreomacular traction

Neil K Jairath; Yannis M Paulus; Angela Yim; Yunshu Zhou; Bela J Parekh; Ruple Jairath; David C Musch; Julie M Rosenthal

doi:10.1371/journal.pone.0272333

Intra- and post-operative risk of retinal breaks during vitrectomy for macular hole and vitreomacular traction

PLoS One. 2022 Aug 11;17(8):e0272333. doi: 10.1371/journal.pone.0272333. eCollection 2022.

Authors

Neil K Jairath¹, Yannis M Paulus^{1

2}, Angela Yim¹, Yunshu Zhou¹, Bela J Parekh¹, Ruple Jairath¹, David C Musch^{1

3}, Julie M Rosenthal¹

Affiliations

¹ Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, United States of America.
² Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
³ Department of Epidemiology, University of Michigan, Ann Arbor, MI, United States of America.

Abstract

Background/objective: To evaluate the development of intra- and post-operative retinal breaks after pars plana vitrectomy (PPV) for macular hole (MH) and/or vitreomacular traction (VMT).

Subjects/methods: Medical records of patients who underwent PPV at Kellogg Eye Center between 1/1/2005-6/30/2018, were evaluated in three groups: group 1, MH/VMT (n = 136); group 2, epiretinal membrane (ERM) without VMT (n = 270); and group 3, diagnostic vitrectomy (DV) or vitreous opacities (n = 35). Statistical analyses were conducted using SAS.

Results: 20.6% of patients with MH/VMT, 8.5% of patients with ERM, and 5.7% of patients with DV or vitreous opacities had either intra-operative or post-operative breaks. Indication of MH/VMT versus ERM was a significant predictor for this outcome (p = .0112). The incidence of retinal breaks was higher in operations using 23-gauge versus 25-gauge PPV (25.0% vs. 7.4%, p < .0001).

Conclusions: The presence of MH and/or VMT is a significant risk factor for retinal breaks from PPV, as is use of 23-gauge vitrectomy.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Epiretinal Membrane* / diagnosis
Epiretinal Membrane* / surgery
Humans
Retinal Perforations* / surgery
Retrospective Studies
Tomography, Optical Coherence
Traction
Vision Disorders / surgery
Vitrectomy / adverse effects

Grants and funding

This research was funded the National Eye Institute grant number 1K08EY027458 (YMP). This research was also supported by an unrestricted departmental grant from Research to Prevent Blindness to the University of Michigan Department of Ophthalmology and Visual Sciences. The sponsor or funding organization had no role in the design or conduct of this research.