Relationship between the cross-sectional area of the lumbar dural sac and lower urinary tract symptoms: A population-based cross-sectional study

Tetsushi Oyama; Kanichiro Wada; Kazushige Koyama; Gentaro Kumagai; Sunao Tanaka; Toru Asari; Atsushi Imai; Teppei Okamoto; Shingo Hatakeyama; Songee Jung; Yoshikuni Sugimura; Chikara Ohyama; Yasuyuki Ishibashi

doi:10.1371/journal.pone.0271479

Relationship between the cross-sectional area of the lumbar dural sac and lower urinary tract symptoms: A population-based cross-sectional study

PLoS One. 2022 Aug 11;17(8):e0271479. doi: 10.1371/journal.pone.0271479. eCollection 2022.

Affiliations

¹ Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
² Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
³ Department of Digital Nutrition and Health Sciences, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
⁴ Department of Microbial Flora and Health Science, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

Abstract

This study aimed to investigate the relationship between the cross-sectional area of the dural sac (DCSA) and lower urinary tract symptoms (LUTS). This study included 270 Japanese participants from a community health check-up in 2016. Overactive bladder (OAB) was diagnosed during the assessment of LUTS. The smallest DCSA of each participant was defined as the minimum DCSA (mDCSA). The cutoff size of the mDCSA in OAB was evaluated using receiver operating characteristic analysis. Multiple logistic regression analyses were performed to identify the independent risk factors for OAB, and a scoring system was developed for estimating these. The prevalence of OAB was 11.1%. Age and low back pain visual analogue scale (LBP VAS) scores were significantly higher, and the mean mDCSA was significantly lower in participants with OAB than in those without. The cutoff size of mDCSA in OAB was 69 mm2. There were significant correlations between OAB and age, LBP VAS score, and mDCSA<70 mm2. Lumbar spinal stenosis (LSS) should be considered a cause of LUTS when mDCSA is <69 mm2. Assessing the mDCSA with age and LBP VAS score was more valuable in detecting LUTS in LSS than the mDCSA alone.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cross-Sectional Studies
Humans
Lower Urinary Tract Symptoms* / diagnosis
Lower Urinary Tract Symptoms* / epidemiology
Prevalence
Spinal Stenosis*
Urinary Bladder, Overactive* / diagnosis
Urinary Bladder, Overactive* / epidemiology

Grants and funding

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This study was supported in part by a Grant-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan (No. 18200044), the Japanese Society for the Promotion of Science (No.21500676), a Health and Labour Sciences Research Grant by JOA Subsidized Science Project Research from the Japanese Orthopaedic Association (No. 2015-02), and the Iwaki Health Promotion Project Center of Innovation Program (No. JPMJCE1302).