Analysis of pupil size by repeat dilation at shrinkage stage

Int Ophthalmol. 2022 Sep;42(9):2645-2649. doi: 10.1007/s10792-022-02235-3. Epub 2022 Aug 10.

Abstract

Purpose: To compare the pupil size of the original mydriasis and repeat mydriasis at the pupil shrinkage stage.

Methods: Randomized prospective study. In total, 60 eyes of 30 patients aged 50-70 with age-related cataracts were included. Pupil sizes were measured by the Sirius system before mydriasis, after the first batch of mydriasis, and after the second batch of mydriasis which was 5 h later. Statistical analysis was performed using MedCalc statistical software version 20.0.3 RESULTS: The pupil size of the second batch of mydriasis 5 h later was smaller than the first batch of mydriasis (3.94 ± 0.88 mm vs 5.12 ± 0.96 mm, P < 0.0001).

Conclusions: Less efficiency repeat mydriasis several hours later compared with original mydriasis in our study suggests that preparation of mydriasis at an appropriate time is necessary for ophthalmological operations. The effect of repeat mydriasis again by tropicamide at the shrinkage stage still needs to be explored.

Keywords: Cataract surgery; Compound tropicamide eyedrops; Mydriasis; Pupil size.

MeSH terms

  • Dilatation
  • Humans
  • Mydriasis*
  • Mydriatics*
  • Phenylephrine
  • Prospective Studies
  • Pupil* / physiology
  • Tropicamide

Substances

  • Mydriatics
  • Phenylephrine
  • Tropicamide