The heart and SARS-CoV-2

Med Clin (Barc). 2022 Nov 11;159(9):440-446. doi: 10.1016/j.medcli.2022.07.002. Epub 2022 Jul 20.
[Article in English, Spanish]

Abstract

SARS-CoV-2 is currently causing a persistent COVID-19 pandemic, which poses a risk of causing long-term cardiovascular sequels in the population. The viral mechanism of cell infection through the angiotensin 2 converter enzyme receptor and the limited antiviral innate immune response are the suspected causes for a more frequent cardiovascular damage in SARS-CoV-2 infection. Knowledge of the appearance during acute infection of other cardiac conditions beyond the classical myocarditis and pericarditis, the long-term cardiac manifestations (persistent COVID-19), and the increased incidence of myocarditis and pericarditis after vaccination is of special interest in order to offer our patients best practices based on current scientific evidence.

Keywords: Afectación cardiovascular; COVID persistente; COVID-19; COVID-19 vaccine; Cardiovascular manifestations; Persistent COVID; SARS-CoV-2; Vacunación COVID-19.

Publication types

  • Review

MeSH terms

  • Angiotensin-Converting Enzyme 2
  • COVID-19*
  • Humans
  • Myocarditis* / diagnosis
  • Myocarditis* / epidemiology
  • Myocarditis* / etiology
  • Pandemics
  • Pericarditis*
  • SARS-CoV-2

Substances

  • Angiotensin-Converting Enzyme 2