Multiple instance convolutional neural network for gallbladder assessment from laparoscopic images

Int J Med Robot. 2022 Dec;18(6):e2445. doi: 10.1002/rcs.2445. Epub 2022 Aug 16.

Abstract

Background: We present an artificial intelligence framework for vascularity classification of the gallbladder (GB) wall from intraoperative images of laparoscopic cholecystectomy (LC).

Methods: A two-stage Multiple Instance Convolutional Neural Network is proposed. First, a convolutional autoencoder is trained to extract feature representations from 4585 patches of GB images. The second model includes a multi-instance encoder that fetches random patches from a GB region and outputs an equal number of embeddings that feed a multi-input classification module, which employs pooling and self-attention mechanisms, to perform prediction.

Results: The evaluation was performed on 234 GB images of low and high vascularity from 68 LC videos. Thorough comparison with various state-of-the-art multi-instance and single-instance learning algorithms was performed for two experimental tasks: image- and video-level classification. The proposed framework shows the best performance with accuracy 92.6%-93.2% and F1 93.5%-93.9%, close to the agreement of two expert evaluators (94%).

Conclusions: The proposed technique provides a novel approach to classify LC operations with respect to the vascular pattern of the GB wall.

Keywords: CNN; artificial intelligence; deep learning; gallbladder; laparoscopic cholecystectomy; multiple instance.

MeSH terms

  • Algorithms
  • Artificial Intelligence*
  • Gallbladder
  • Humans
  • Laparoscopy*
  • Neural Networks, Computer