Synthesis of silver nanoparticles using Eucommia ulmoides extract and their potential biological function in cosmetics

Jinfeng Xi; Wenjie Kan; Yan Zhu; Shengwei Huang; Lifang Wu; Jun Wang

doi:10.1016/j.heliyon.2022.e10021

Synthesis of silver nanoparticles using Eucommia ulmoides extract and their potential biological function in cosmetics

Heliyon. 2022 Jul 29;8(8):e10021. doi: 10.1016/j.heliyon.2022.e10021. eCollection 2022 Aug.

Authors

Jinfeng Xi^{1

2}, Wenjie Kan³, Yan Zhu^{1

2}, Shengwei Huang⁴, Lifang Wu^{1

2

5}, Jun Wang^{1

2

5}

Affiliations

¹ The Center for Ion Beam Bioengineering and Green Agriculture, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, Anhui, China.
² University of Science and Technology of China, Hefei 230026, Anhui, China.
³ Institutes of Physical Science and Information Technology, Anhui University, Hefei 230601, China.
⁴ Institute of Biomedical and Health Science, School of Life and Health Science, Anhui Science and Technology University, Fengyang, Anhui, 233100, China.
⁵ Zhongke Taihe Experimental Station, Taihe 236626, Anhui, China.

Abstract

Silver nanoparticles (AgNPs) synthesized from plant extracts have recently emerged as a rapidly growing field with numerous applications in pharmaceutical and clinical contexts. The purpose of this research is to come up with a novel method for the biosynthesis of silver nanoparticles that use Eucommia ulmoides leaf extract as a reducing agent. The synthesis of AgNPs was confirmed using UV-vis spectroscopy, and the properties of AgNPs were characterized using Transmission Electron Microscope, Fourier Infrared Spectrometer, X-ray diffraction, Thermogravimetric Analysis, and Zeta potential. The results showed that the AgNPs exhibited a characteristic absorption peak at 430 nm, their diameter ranged from 4 nm to 52 nm, and C, O, and Cl elements, which might represent flavonoids and phenolic components absorbed on the surface of AgNPs. The zeta potential of AgNPs was found to be -30.5 mV, which indicates repulsion among AgNPs and they have good dispersion stability. AgNPs have been found to suppress the tyrosinase activity both in mushroom tyrosinase and A375 cells, as well as diminish ROS formation in HaCat cells. According to this study, AgNPs is a novel material that can enhance skin health by preventing melanin development.

Keywords: AgNPs; Antioxidant activity; Eucommia ulmoides; Tyrosinase activity.