Pheochromocytoma-Induced Tako-Tsubo Syndrome: An Uncommon Presentation

J Emerg Med. 2022 Jul;63(1):e1-e6. doi: 10.1016/j.jemermed.2022.04.025. Epub 2022 Aug 6.

Abstract

Background: A pheochromocytoma-induced tako-tsubo syndrome is a life-threatening complication of the rare endocrinological disease. The association between the two syndromes is known, though seldom reported in literature, but the categorization is still debated.

Case report: In this article, we provide two examples of clinical presentation of this rare condition, its diagnosis using point-of-care ultrasound, its management in the emergency department, and finally, a literature review. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: In case of a tako-tsubo syndrome-like myocardial dysfunction in a patient with unknown medical history, or recorded hypertensive or tachycardic peaks, a point-of-care ultrasound scan extended to the kidneys could help evaluate for a reversible underlying trigger cause such as pheochromocytoma.

Keywords: POCUS; emergency department; pheochromocytoma; tako-tsubo syndrome; ultrasound.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adrenal Gland Neoplasms* / complications
  • Adrenal Gland Neoplasms* / diagnosis
  • Electrocardiography
  • Emergency Service, Hospital
  • Humans
  • Pheochromocytoma* / complications
  • Pheochromocytoma* / diagnosis
  • Syndrome
  • Takotsubo Cardiomyopathy* / diagnosis
  • Takotsubo Cardiomyopathy* / etiology