RETRACTED: Potential of β-elemene induced ferroptosis through Pole2-mediated p53 and PI3K/AKT signaling in lung cancer cells

Chem Biol Interact. 2022 Sep 25:365:110088. doi: 10.1016/j.cbi.2022.110088. Epub 2022 Aug 6.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. After a thorough investigation, the Editor has concluded that the acceptance of this article was partly based upon the positive advice of one illegitimate reviewer report. The report was submitted from an email account which was provided to the journal as a suggested reviewer during the submission of the article. Although purportedly a real reviewer account, the Editor has concluded that this was not of an appropriate, independent reviewer. Further inquiry revealed that the name of the author Anshoo Malhotra was added after the acceptance of the article without notifying the author and the handling Editor, which is contrary to the journal policy on changes to authorship. This manipulation of the peer-review process represents a clear violation of the fundamentals of peer review, our publishing policies, and publishing ethics standards. Apologies are offered to the reviewer whose identity was assumed and to the readers of the journal that this deception was not detected during the submission process.

Keywords: Lung cancer; PI3K/AKT; Pole2; β‐elemene.

Publication types

  • Retracted Publication

MeSH terms

  • Cell Line, Tumor
  • DNA Polymerase II / metabolism
  • Ferroptosis*
  • Humans
  • Iron / metabolism
  • Lung / pathology
  • Lung Neoplasms* / pathology
  • Phosphatidylinositol 3-Kinases / metabolism
  • Proto-Oncogene Proteins c-akt / metabolism
  • Reactive Oxygen Species / metabolism
  • Sesquiterpenes* / pharmacology
  • Tumor Suppressor Protein p53

Substances

  • Reactive Oxygen Species
  • Sesquiterpenes
  • Tumor Suppressor Protein p53
  • beta-elemene
  • Iron
  • Proto-Oncogene Proteins c-akt
  • DNA Polymerase II
  • POLE2 protein, human