Evans Syndrome Presenting as an Atypical Complication of SARS-CoV-2 Vaccination

Cureus. 2022 Jul 6;14(7):e26602. doi: 10.7759/cureus.26602. eCollection 2022 Jul.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has drastically affected our daily lives, causing millions of deaths worldwide. The early and late complications of this infection are being increasingly revealed on a regular basis; however, an important brake on the spread and especially the lethality of the disease has been guaranteed by the introduction of mRNA-based and viral vector-based COVID-19 Vaccines. Also, an increasing number of adverse effects of the vaccination have been reported to specific pharmacovigilance boards, most of them totally non-serious events that are resolved within one to three days after the administration of the vaccine. In this report, we present a case of Evans syndrome (ES) secondary to SARS-CoV-2 vaccination in an 85-year-old male patient. To the best of our knowledge, this is the first case of ES caused by the COVID-19 vaccination to be reported in the literature.

Keywords: autoimmune haemolytic anaemia; evans syndrome; immune thrombocytopenia; sars-cov 2; vaccination.

Publication types

  • Case Reports

Grants and funding

AIL Caserta ODV Valentina Picazio Foundation paid for publication fees.