Antibiotic resistance in Enterobacter hormaechei

Ting-Kuang Yeh; Hsueh-Ju Lin; Po-Yu Liu; Jui-Hsing Wang; Po-Ren Hsueh

doi:10.1016/j.ijantimicag.2022.106650

Antibiotic resistance in Enterobacter hormaechei

Int J Antimicrob Agents. 2022 Oct;60(4):106650. doi: 10.1016/j.ijantimicag.2022.106650. Epub 2022 Aug 4.

Authors

Ting-Kuang Yeh¹, Hsueh-Ju Lin², Po-Yu Liu³, Jui-Hsing Wang⁴, Po-Ren Hsueh⁵

Affiliations

¹ Division of Infectious Disease, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
² Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
³ Division of Infectious Disease, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; RongHsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan; PhD Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan.
⁴ Division of Infectious Disease, Department of Internal Medicine, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan; Department of Internal Medicine, School of Medicine, Tzu Chi University, Hualien, Taiwan. Electronic address: u702026@gmail.com.
⁵ Departments of Laboratory Medicine and Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan; PhD Programme for Aging, School of Medicine, China Medical University, Taichung, Taiwan; Department of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: hsporen@gmail.com.

PMID: 35934231
DOI: 10.1016/j.ijantimicag.2022.106650

Abstract

Enterobacter hormaechei, a member of the Enterobacter cloacae complex, has emerged as an important pathogen in healthcare-associated infections. Advancements in phylogenetic analyses and whole-genome sequencing techniques have led to the identification of E. hormaechei in numerous locations worldwide. The emergence of antibiotic-resistant E. hormaechei isolates, including those that produce extended-spectrum β-lactamases (ESBLs), AmpC β-lactamases and carbapenemases, has been reported worldwide. In this article, we review the different resistance genes of antibiotic-resistant E. hormaechei.

Keywords: Antibiotic resistance; Carbapenemase; ESBL; Enterobacter cloacae complex; Enterobacter hormaechei; β-Lactamase.

Publication types

Review

MeSH terms

Anti-Bacterial Agents / pharmacology
Bacterial Proteins / genetics
Drug Resistance, Microbial
Enterobacter
Enterobacter cloacae
Enterobacteriaceae Infections* / drug therapy
Humans
Microbial Sensitivity Tests
Phylogeny
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Bacterial Proteins
beta-Lactamases

Supplementary concepts

Enterobacter hormaechei