Ocular biometric changes following unilateral cataract surgery in children

PLoS One. 2022 Aug 5;17(8):e0272369. doi: 10.1371/journal.pone.0272369. eCollection 2022.

Abstract

Purpose: To analyze ocular biometric changes following unilateral cataract surgery in children.

Methods: A total of 57 children aged under 13 years who underwent unilateral cataract surgery were analyzed. Groups were classified according to their age at surgery: group I (age <3), II (3≤ age <6), III (6≤ age <9), and IV (age ≥9). The myopic shift, axial growth, and corneal curvature changes were compared between the pseudophakic eyes and the fellow phakic eyes.

Results: During 7.81 ± 4.39 years, the overall myopic shift (D) and the rate of myopic shift (D/year) were significantly higher at -3.25 ± 3.21 D and -0.45 ± 0.44 D/year in the pseudophakic eyes than -1.78 ± 2.10 D and -0.22 ± 0.29 D/year in the fellow phakic eyes (P = 0.01, 0.004). Group I (-1.14 ± 0.66 vs -0.02 ± 0.45 D/year) and group II (-0.63 ± 0.37 vs -0.31 ± 0.29 D/year) showed significantly higher rate of myopic shift in the pseudophakic eyes than in the phakic eyes. The rate of myopic shift in the pseudophakic eyes decreased in the older age groups (P = 0.001). There was no significant between-eye difference in the changes in axial length and keratometric values postoperatively.

Conclusion: Following unilateral cataract surgery, a significant postoperative myopic shift was noticed in the pseudophakic eyes compared to the fellow phakic eyes in groups under 6 years old. Postoperative myopic shift and the resultant anisometropia should be considered when selecting the optimal power of IOL in young children requiring unilateral cataract surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biometry
  • Cataract Extraction*
  • Cataract*
  • Child
  • Child, Preschool
  • Cornea
  • Follow-Up Studies
  • Humans
  • Lens Implantation, Intraocular
  • Myopia* / surgery
  • Refraction, Ocular

Grants and funding

This study was supported to SHP, the corresponding author, by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, & Future Planning (NRF-2016R1C1B1016590) and by the Department of Ophthalmology, College of Medicine, Catholic University of Korea, Man-Soo Kim Research Fund, 2022. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.