Incidental littoral cell angioma of the spleen: cross-sectional imaging findings and review of the literature

Pier Paolo Arcuri; Stefano Taglianetti; Barbara Vavalà; Caterina Battaglia; Domenico Laganà; Francesco Manti

doi:10.1016/j.radcr.2022.06.063

Incidental littoral cell angioma of the spleen: cross-sectional imaging findings and review of the literature

Radiol Case Rep. 2022 Jul 28;17(10):3545-3550. doi: 10.1016/j.radcr.2022.06.063. eCollection 2022 Oct.

Authors

Pier Paolo Arcuri¹, Stefano Taglianetti², Barbara Vavalà¹, Caterina Battaglia², Domenico Laganà², Francesco Manti²

Affiliations

¹ Radiology Unit, Department of Radiology, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
² Radiology Unit, Department of Experimental and Clinical Medicine, "Magna Graecia" University, Catanzaro, Italy.

Abstract

Littoral cell angioma (LCA) is a primary splenic hemangioma found mostly in normal red sinus shore cells of the reticuloendothelial cell system of the spleen. In most cases is benign, but sometimes malignancies have been reported. This tumor displayed epithelial and histiocytic properties based on its cell of origin, splenic littoral cells. In this case report, we will describe a case of a 21-year-male presenting with an incidentally discovered LCA illustrated by cross-sectional imaging techniques, highlighting how the diffusional sequence and the positron emission tomography study, thanks to their greater specificity, have contributed to reaching a correct diagnostic orientation more than dynamic studies with contrast agent in both computed tomography and magnetic resonance.

Keywords: Diffusion-MRI; FDG-PET/CT; Littoral cell angioma; Spleen.

Publication types

Case Reports