Betalains: colours for human health

Nat Prod Res. 2023 May;37(10):1746-1765. doi: 10.1080/14786419.2022.2106481. Epub 2022 Aug 3.

Abstract

In the last years, the use of natural phytochemical compounds as protective agents in the prevention and treatment of obesity and the related-metabolic syndrome has gained much attention worldwide. Different studies have shown health benefits for many vegetables such Opuntia ficus-indica and Beta vulgaris and their pigments collectively referred as betalains. Betalains exert antioxidative, anti-inflammation, lipid lowering, antidiabetic and anti-obesity effects. This review summarizes findings in the literature and highlights the therapeutic potential of betalains and their natural source as valid alternative for supplementation in obesity-related disorders treatment. Further research is needed to establish the mechanisms through which these natural pigments exert their beneficial effects and to translate the promising findings from animal models to humans.

Keywords: Betalains; Opuntia ficus indica; metabolic syndrome; obesity.

Publication types

  • Review

MeSH terms

  • Animals
  • Antioxidants / analysis
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Betalains* / analysis
  • Betalains* / pharmacology
  • Betalains* / therapeutic use
  • Color
  • Fruit / chemistry
  • Humans
  • Opuntia* / chemistry
  • Plant Extracts / chemistry

Substances

  • Betalains
  • Plant Extracts
  • Antioxidants