Memantine targets glutamate receptors in atrial cardiomyocytes to prevent and treat atrial fibrillation

Duanyang Xie; Ke Xiong; Xuling Su; Guanghua Wang; Luxin Wang; Qicheng Zou; Caihong Zhang; Yuting Cao; Yi Liu; Yi-Han Chen

doi:10.1038/s41421-022-00429-8

Memantine targets glutamate receptors in atrial cardiomyocytes to prevent and treat atrial fibrillation

Cell Discov. 2022 Aug 2;8(1):76. doi: 10.1038/s41421-022-00429-8.

Authors

Duanyang Xie^#^{1

2

3}, Ke Xiong^#^{1

2

3}, Xuling Su^#^{2

3}, Guanghua Wang^#^{2

3}, Luxin Wang^#^{1

2

3}, Qicheng Zou^{1

2

3}, Caihong Zhang^{2

4}, Yuting Cao^{2

4}, Yi Liu^{1

2

3}, Yi-Han Chen^{5

6

7

8

9}

Affiliations

¹ Department of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
² Key Laboratory of Arrhythmias of the Ministry of Education of China, Tongji University School of Medicine, Shanghai, China.
³ Institute of Medical Genetics, Tongji University, Shanghai, China.
⁴ Jinzhou Medical University, Jinzhou, Liaoning, China.
⁵ Department of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China. yihanchen@tongji.edu.cn.
⁶ Key Laboratory of Arrhythmias of the Ministry of Education of China, Tongji University School of Medicine, Shanghai, China. yihanchen@tongji.edu.cn.
⁷ Institute of Medical Genetics, Tongji University, Shanghai, China. yihanchen@tongji.edu.cn.
⁸ Department of Pathology and Pathophysiology, Tongji University School of Medicine, Shanghai, China. yihanchen@tongji.edu.cn.
⁹ Research Units of Origin and Regulation of Heart Rhythm, Chinese Academy of Medical Sciences, Shanghai, China. yihanchen@tongji.edu.cn.

^# Contributed equally.

No abstract available

Publication types

Letter

Grants and funding

82088101 and 81930013/National Natural Science Foundation of China (National Science Foundation of China)