Smart gene therapeutics for selective targeting of myofibroblasts derived from hepatic stellate cells and limited expression under inflamed conditions

Dodam Moon; Hyomin Park; Injoo Hwang; Areum Cha; Hyunji Yun; Jaewon Lee; Sung-Hye Park; Eun Ju Lee; Hyo-Soo Kim

doi:10.1002/ctm2.991

Smart gene therapeutics for selective targeting of myofibroblasts derived from hepatic stellate cells and limited expression under inflamed conditions

Clin Transl Med. 2022 Aug;12(8):e991. doi: 10.1002/ctm2.991.

Authors

Dodam Moon^{1

2}, Hyomin Park^{1

2}, Injoo Hwang^{1

2}, Areum Cha^{2

3}, Hyunji Yun^{2

3}, Jaewon Lee², Sung-Hye Park⁴, Eun Ju Lee^{2

3}, Hyo-Soo Kim^{1

2

3}

Affiliations

¹ Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
² Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
³ Interdisciplinary Program in Stem Cell Biology, Seoul National University of Medicine, Seoul, Republic of Korea.
⁴ Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea.

No abstract available

Publication types

Letter

MeSH terms

Hepatic Stellate Cells* / metabolism
Hepatic Stellate Cells* / pathology
Humans
Liver Cirrhosis / metabolism
Liver Cirrhosis / pathology
Myofibroblasts* / metabolism
Myofibroblasts* / pathology