Potential Impact of COVID-19 on Female Reproductive Health

JBRA Assist Reprod. 2023 Mar 30;27(1):92-96. doi: 10.5935/1518-0557.20220019.

Abstract

COVID-19 has emerged as the biggest pandemic of the world of all times. Its death toll is rising globally. COVID-19 mostly affects the lungs because the virus enters the host cells via the receptor for the ACE2 enzyme, which is also present in other organs of the human body. ACE2 plays the main role in the degradation of Ang II, resulting in the formation of angiotensin 1-7 (Ang 1-7) which maintains the level of Ang II. This communication gives an assessment of reproductive system functioning and its effects by the COVID-19 exposure. It is important to maintain the wellbeing for healthy nourishment of the fetus and safe delivery along with post health issues. ACE2 enzyme metabolism is expressed in the female reproductive system, and it may be potential target of COVID-19 exposure.

Keywords: COVID-19; angiotensin converting enzyme; female reproductive.

Publication types

  • Review

MeSH terms

  • Angiotensin-Converting Enzyme 2
  • COVID-19*
  • Female
  • Humans
  • Peptidyl-Dipeptidase A / metabolism
  • Reproductive Health
  • SARS-CoV-2 / metabolism

Substances

  • Peptidyl-Dipeptidase A
  • Angiotensin-Converting Enzyme 2