On-Chip Chemical Synthesis Using One-Step 3D Printed Polyperfluoropolyether

Chem Ing Tech. 2022 Jul;94(7):975-982. doi: 10.1002/cite.202200013. Epub 2022 Apr 25.

Abstract

Three-dimensional (3D) printing has already shown its high relevance for the fabrication of microfluidic devices in terms of precision manufacturing cycles and a wider range of materials. 3D-printable transparent fluoropolymers are highly sought after due to their high chemical and thermal resistance. Here, we present a simple one-step fabrication process via stereolithography of perfluoropolyether dimethacrylate. We demonstrate successfully printed microfluidic mixers with 800 µm circular channels for chemistry-on-chip applications. The printed chips show chemical, mechanical, and thermal resistance up to 200 °C, as well as high optical transparency. Aqueous and organic reactions are presented to demonstrate the wide potential of perfluoropolyether dimethacrylate for chemical synthesis.

Keywords: Additive manufacturing; Chemical synthesis; Fluorinated materials; Microfluidics.