DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP-2*) in Atlantic salmon (Salmo salar L.)

J Fish Biol. 2022 Nov;101(5):1371-1374. doi: 10.1111/jfb.15182. Epub 2022 Aug 14.

Abstract

A non-synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP-dependent mMEP-2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mobility of the two allozyme alleles, whereas allozyme and SNP assays revealed genotyping concordance in 257 of 258 individuals. A single mismatch, homozygous allozyme vs. heterozygote SNP, suggests the presence of a second, less common null allele.

Keywords: SNP; allozyme; malic enzyme; population; selection.

MeSH terms

  • Alleles
  • Animals
  • DNA
  • Isoenzymes
  • Polymorphism, Single Nucleotide
  • Salmo salar* / genetics

Substances

  • Isoenzymes
  • DNA