Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection

Yanqiu Mei; Xiaofeng Lin; Chen He; Weijia Zeng; Yan Luo; Chenghao Liu; Zhehao Liu; Min Yang; Ying Kuang; Qitong Huang

doi:10.3389/fbioe.2022.952510

Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection

Front Bioeng Biotechnol. 2022 Jul 15:10:952510. doi: 10.3389/fbioe.2022.952510. eCollection 2022.

Authors

Yanqiu Mei¹, Xiaofeng Lin^{1

2}, Chen He², Weijia Zeng², Yan Luo², Chenghao Liu², Zhehao Liu^{1

2}, Min Yang^{1

2}, Ying Kuang^{1

2}, Qitong Huang^{1

2}

Affiliations

¹ Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province, Key Laboratory of Biomedical Sensors of Ganzhou, School of Public Health and Health Management, School of Medical and Information Engineering, Gannan Medical University, Ganzhou, China.
² Oil-Tea in Medical Health Care and Functional Product Development Engineering Research Center in Jiangxi, The Science Research Center, School of Pharmacy, Gannan Medical University, Ganzhou, China.

Abstract

Coronavirus disease 19 (COVID-19) is still a major public health concern in many nations today. COVID-19 transmission is now controlled mostly through early discovery, isolation, and therapy. Because of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the contributing factor to COVID-19, establishing timely, sensitive, accurate, simple, and budget detection technologies for the SARS-CoV-2 is urgent for epidemic prevention. Recently, several electrochemical DNA biosensors have been developed for the rapid monitoring and detection of SARS-CoV-2. This mini-review examines the latest improvements in the detection of SARS-COV-2 utilizing electrochemical DNA biosensors. Meanwhile, this mini-review summarizes the problems faced by the existing assays and puts an outlook on future trends in the development of new assays for SARS-CoV-2, to provide researchers with a borrowing role in the generation of different assays.

Keywords: COVID-19; SARS-CoV-2; electrochemical DNA biosensors; nucleic acid detection; virus/protein detection.

Publication types

Review