In modern systems, from brain neural networks to social group networks, pairwise interactions are not sufficient to express higher-order relationships. The smallest unit of their internal function is not composed of a single functional node but results from multiple functional nodes acting together. Therefore, researchers adopt the hypergraph to describe complex systems. The targeted attack on random hypergraph networks is still a problem worthy of study. This work puts forward a theoretical framework to analyze the robustness of random hypergraph networks under the background of a targeted attack on nodes with high or low hyperdegrees. We discovered the process of cascading failures and the giant connected cluster (GCC) of the hypergraph network under targeted attack by associating the simple mapping of the factor graph with the hypergraph and using percolation theory and generating function. On random hypergraph networks, we do Monte-Carlo simulations and find that the theoretical findings match the simulation results. Similarly, targeted attacks are more effective than random failures in disintegrating random hypergraph networks. The threshold of the hypergraph network grows as the probability of high hyperdegree nodes being deleted increases, indicating that the network's resilience becomes more fragile. When considering real-world scenarios, our conclusions are validated by real-world hypergraph networks. These findings will help us understand the impact of the hypergraph's underlying structure on network resilience.