The use of microfluidic devices in studies of differential sperm chemotaxis

Jake A Penny; Rowan A Lymbery; Jonathan P Evans; Craig D H Sherman; Xavier A Conlan

doi:10.1016/j.tibtech.2022.06.014

The use of microfluidic devices in studies of differential sperm chemotaxis

Trends Biotechnol. 2022 Oct;40(10):1144-1147. doi: 10.1016/j.tibtech.2022.06.014. Epub 2022 Jul 25.

Authors

Jake A Penny¹, Rowan A Lymbery², Jonathan P Evans², Craig D H Sherman³, Xavier A Conlan³

Affiliations

¹ Deakin University, School of Life and Environmental Sciences, Geelong, Victoria 3216, Australia. Electronic address: jpenny@lincoln.ac.uk.
² School of Biological Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
³ Deakin University, School of Life and Environmental Sciences, Geelong, Victoria 3216, Australia.

PMID: 35902284
DOI: 10.1016/j.tibtech.2022.06.014

Abstract

Differential sperm chemotaxis describes differences among male-female pairings in chemotactic responses of sperm to egg (or female)-derived chemical attractants. Microfluidic devices provide powerful platforms in which to study this complex gamete interaction. Here, we describe key challenges and potential solutions in applying this state-of-the-art technique to differential sperm chemotaxis.

Keywords: microfluidics; multidisciplinary; rapid analysis; sexual selection; sperm chemotaxis; sperm motility.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chemotaxis* / physiology
Female
Humans
Lab-On-A-Chip Devices*
Male
Semen
Spermatozoa / physiology