Function and Application of Flavonoids in the Breast Cancer

Int J Mol Sci. 2022 Jul 13;23(14):7732. doi: 10.3390/ijms23147732.

Abstract

Breast cancer is one of the top causes of death, particularly among women, and it affects many women. Cancer can also be caused by various factors, including acquiring genetic alteration. Doctors use radiation to detect and treat breast cancer. As a result, breast cancer becomes radiation-resistant, necessitating a new strategy for its treatment. The approach discovered by the researchers is a flavonoid, which is being researched to see if it might help treat radiation-resistant breast cancer more safely than an approved medicine already being used in the field. As a result, this study focuses on the role of flavonoids in breast cancer suppression, breast cancer gene anomalies, and the resulting apoptotic mechanism.

Keywords: apoptosis; breast cancer; flavonoid.

Publication types

  • Review

MeSH terms

  • Apoptosis
  • Breast
  • Breast Neoplasms* / drug therapy
  • Breast Neoplasms* / genetics
  • Female
  • Flavonoids* / pharmacology
  • Flavonoids* / therapeutic use
  • Humans

Substances

  • Flavonoids

Grants and funding

This study was supported by the National Research Foundation of Korea funded by Ministry of Science and ICT (grant no. 2020R1A2B5B01001807).