Background and objective: The segmentation and visualization of liver vessels in 3D CT images are essential for computer-aided diagnosis and preoperative planning of liver diseases. Due to the irregular structure of liver vessels and image noise, accurate extraction of liver vessels is difficult. In particular, accurate segmentation of small vessels is always a challenge, as multiple single down-sampling usually results in a loss of information.
Methods: In this paper, we propose a hierarchical progressive multiscale learning network (HPM-Net) framework for liver vessel segmentation. Firstly, the hierarchical progressive multiscale learning network combines internal and external progressive learning methods to learn semantic information about liver vessels at different scales by acquiring receptive fields of different sizes. Secondly, to better capture vessel features, we propose a dual-branch progressive 3D Unet, which uses a dual-branch progressive (DBP) down-sampling strategy to reduce the loss of detailed information in the process of network down-sampling. Finally, a deep supervision mechanism is introduced into the framework and backbone network to speed up the network convergence and achieve better training of the network.
Results: We conducted experiments on the public dataset 3Dircadb for liver vessel segmentation. The average dice coefficient and sensitivity of the proposed method reached 75.18% and 78.84%, respectively, both higher than the original network.
Conclusion: Experimental results show that the proposed hierarchical progressive multiscale network can accurately segment the labeled liver vessels from the CT images.
Keywords: Deep learning; Deep supervision mechanism; Dual-branch progressive 3D Unet; Hierarchical progressive; Liver vessels segmentation.
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