A meta-analysis and meta-regression analysis of the global prevalence of obsessive-compulsive personality disorder

Marina Junqueira Clemente; Anderson Sousa Martins Silva; Maria Olivia Pozzolo Pedro; Henrique Soares Paiva; Cintia de Azevedo Marques Périco; Julio Torales; Antonio Ventriglio; João Maurício Castaldelli-Maia

doi:10.1016/j.heliyon.2022.e09912

A meta-analysis and meta-regression analysis of the global prevalence of obsessive-compulsive personality disorder

Heliyon. 2022 Jul 12;8(7):e09912. doi: 10.1016/j.heliyon.2022.e09912. eCollection 2022 Jul.

Affiliations

¹ Health Secretariat of São Bernardo do Campo, São Bernardo do Campo, SP, Brazil.
² Department of Psychiatry, Medical School, University of São Paulo, São Paulo, SP, Brazil.
³ Department of Neuroscience, Medical School, ABC Health University Center, Santo André, SP, Brazil.
⁴ Department of Psychiatry, School of Medical Sciences, National University of Asunción, Asunción, Paraguay.
⁵ Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
⁶ Department of Epidemiology, Columbia Mailman School of Public Health, New York, NY, USA.

Abstract

There is a relative dearth of research on Obsessive-Compulsive Personality Disorder (OCPD), even if it has been recognized for over 100 years. Thus, the present study aims to review the worldwide prevalence of OCPD in different populations. The search was conducted employing the PubMed database of the US National Library of Medicine and Biblioteca Virtual em Saúde (BVS) to detect available studies showing OCPD prevalence rates. All the prevalence rates were extracted and aggregated through random-effects models. Meta-regression and sensitivity analyses were performed. The final sample was composed of 46 articles, including 89,264 individuals. We found that OCPD reports a high prevalence rate, with 6.5% (95%CI = 4.3-9.1%), and reaching even higher among psychiatric and clinical patient population. OCPD has presented stable prevalence rates worldwide throughout the past 28 years. There was no gender-related effect, but OCPD prevalence rates may decrease with age increase. There is a need to investigate personality disorders epidemiology based on the recently updated classification systems (i.e., DSM-5 and ICD-11). The present meta-analysis may suggest that the current diagnostic tools may detect OCPD in a cross-sectional assessment but not throughout the life of the person.

Keywords: Compulsive personality disorder; OCPD; Personality disorders; Prevalence.