Substrate-independent and widely applicable deposition of antibacterial coatings

Abstract

Antibacterial coatings are regarded as a necessary tool to prevent implant-related infections. Substrate-independent and widely applicable coating techniques are gaining significant interest to synthesize different types of antibacterial films, which can be relevant from a fundamental and application-oriented perspective. Plasma polymer- and polydopamine-based antibacterial coatings represent the most widely studied and versatile approaches among these coating techniques. Both single- and dual-functional antibacterial coatings can be fabricated with these approaches and a variety of dual-functional antibacterial coating strategies can still be explored in future work. These coatings can potentially be used for a wide range of different implants (material, shape, and size). However, for most implants, significantly more fundamental knowledge needs to be gained before these coatings can find real-life use.

Keywords: antibacterial coating; plasma polymerization; polydopamine; substrate-independence.