Flagellate dermatitis in bleomycin chemotherapy: a causality?

BMJ Case Rep. 2022 Jul 21;15(7):e249704. doi: 10.1136/bcr-2022-249704.

Abstract

Flagellate dermatitis is a relatively rare reaction to toxicity. It appears as skin lesions with erythematous patches or papules of linear, multiple, flagellate structures. Flagellate dermatitis can be triggered by several causes, which are most commonly associated with bleomycin. This paper reports two cases of flagellate dermatitis, one in a patient with germ cell carcinoma and another in a patient with osteosarcoma who were both diagnosed with flagellate dermatitis after the administration of bleomycin.

Keywords: Dermatology; Skin.

Publication types

  • Case Reports

MeSH terms

  • Bleomycin / adverse effects
  • Dermatitis* / complications
  • Drug Eruptions* / pathology
  • Erythema / complications
  • Humans
  • Immune System Diseases*
  • Neoplasms, Germ Cell and Embryonal* / complications

Substances

  • Bleomycin