Acute Tubular Necrosis and Thrombocytopenia Associated With Rifampin Use: Case Report and Review

Open Forum Infect Dis. 2022 May 17;9(7):ofac258. doi: 10.1093/ofid/ofac258. eCollection 2022 Jul.

Abstract

A case of rifampin-induced acute tubular necrosis requiring hemodialysis in a patient receiving thrice-weekly rifampin with daily dapsone for retreatment of relapsed Hansen's disease is reported. The patient had positive rifampin-dependent antiplatelet antibodies. Case reports of acute renal failure associated with the use of rifampin are summarized.

Keywords: antibodies; renal failure; rifampin.