Patient-reported outcomes following autologous stem cell transplant for patients with multiple myeloma

EJHaem. 2021 Jun 27;2(3):488-492. doi: 10.1002/jha2.231. eCollection 2021 Aug.

Abstract

We evaluated changes in patient-reported outcomes and cognitive function from pre- to 3-6 months post-treatment among 42 newly diagnosed patients with multiple myeloma undergoing transplant with complete data using PROMIS-29. There were statistically significant improvements in physical (p < .001) and mental health (p < .001) but not cognition from pre-treatment to 3-6 month follow-up. Similar results were seen within age or comorbidity strata. Patients with myeloma undergoing transplant experienced generally improved short-term health outcomes with no significant declines in cognition.

Keywords: autologous stem cell transplant; cognitive function; multiple myeloma; patient‐reported outcomes; quality of life.