Subgroup-specific roles of primary cilia in medulloblastoma

Abstract

Here I discuss the study in this issue of Genes & Development by Youn et al. (pp. 737-751), which describes defined and diverse roles of primary cilia in molecularly distinct medulloblastoma subgroups, highlighting once again the importance of designing subgroup-specific therapeutic approaches for this tumor.

Keywords: WNT; cell cycle; cilia; medulloblastoma; translation.