AL-Type Amyloidosis Involving Stomach and Lungs in 99m Tc-DPD Bone Scan

Clin Nucl Med. 2022 Dec 1;47(12):1059-1060. doi: 10.1097/RLU.0000000000004336. Epub 2022 Jul 15.

Abstract

Systemic AL (amyloid light-chain) amyloidosis is a relatively rare disease. 99m Tc-DPD (3,3-diphosphono-1,2-pyrophosphate) bone scan is a highly sensitive diagnostic tool for cardiac amyloidosis of ATTR (transthyretin) type. In AL amyloidosis, there have been some previous reports of extracardiac DPD uptake in liver, kidney, and spleen, but not in stomach. We present 99m Tc-DPD bone scan images of AL-type amyloidosis involving stomach and lung.

MeSH terms

  • Amyloidosis* / diagnostic imaging
  • Cardiomyopathies*
  • Humans
  • Immunoglobulin Light-chain Amyloidosis*
  • Lung / diagnostic imaging
  • Organotechnetium Compounds
  • Stomach
  • Tomography, X-Ray Computed

Substances

  • Organotechnetium Compounds