Case Report: Anterior Scleritis Presenting as a Primary Ocular Manifestation in Multisystem Inflammatory Syndrome in Children With COVID-19

Daisuke Matsubara; Daisuke Tamura; Yuka Kasuya; Yoshitaka Mizobe; Mami Hiwada; Mitsuru Seki; Shinji Makino; Takanori Yamagata

doi:10.3389/fped.2022.943652

Case Report: Anterior Scleritis Presenting as a Primary Ocular Manifestation in Multisystem Inflammatory Syndrome in Children With COVID-19

Front Pediatr. 2022 Jun 27:10:943652. doi: 10.3389/fped.2022.943652. eCollection 2022.

Authors

Daisuke Matsubara¹, Daisuke Tamura¹, Yuka Kasuya², Yoshitaka Mizobe¹, Mami Hiwada¹, Mitsuru Seki¹, Shinji Makino², Takanori Yamagata¹

Affiliations

¹ Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
² Department of Ophthalmology, Jichi Medical University, Shimotsuke, Japan.

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a newly defined hyperinflammatory disease linked to antecedent coronavirus disease 2019. Patients with MIS-C present with various symptoms, and ocular findings such as mild bilateral conjunctivitis are relatively common. However, detailed descriptions of severe ocular reports associated with MIS-C are scarce in the current literature. Here we report a case of MIS-C in a Japanese boy, with severe eye manifestations in the form of anterior scleritis as the primary MIS-C symptom. Detailed ocular examinations by ophthalmologists may be key for clarifying the pathophysiology of MIS-C.

Keywords: COVID-19; Kawasaki disease; case report; conjunctivitis; fundus findings; multisystem inflammatory syndrome in children; ophthalmological examinations; scleritis.

Publication types

Case Reports