Splenic Infarctions in Polycythaemia Vera are Not Always a Catastrophe

Eur J Case Rep Intern Med. 2022 Jun 29;9(6):003370. doi: 10.12890/2022_003370. eCollection 2022.

Abstract

Splenic infarction can occur as an infrequent thrombotic manifestation in polycythaemia vera (PV) and is usually catastrophic. We describe the case of a middle-aged woman who was diagnosed with PV 3 months before she presented to the emergency department with acute limb ischaemia. A splenic infarction detected on diagnostic imaging during her hospital stay was treated conservatively with modification of her hydroxyurea dose along with pain management, without the need for surgery.

Learning points: Multiple splenic infarctions are an uncommon presentation in polycythaemia vera.Patients can present with vague abdominal pain, so a high index of suspicion is necessary and diagnosis is usually radiological.Splenic infarction in polycythaemia patients can be treated successfully with hydroxyurea and pain management with aspirin.

Keywords: PV; infarction; polycythemia vera; spleen.