Photodynamic therapy-a promising treatment of oral mucosal infections

Photodiagnosis Photodyn Ther. 2022 Sep:39:103010. doi: 10.1016/j.pdpdt.2022.103010. Epub 2022 Jul 9.

Abstract

The treatment of oral mucosal infections is increasingly challenging owing to antibiotic resistance. Therefore, alternative antimicrobial strategies are urgently required. Photodynamic therapy (PDT) has attracted attention for the treatment of oral mucosal infections because of its ability to effectively inactivate drug-resistant bacteria, completely heal clinical infectious lesions and usually offers only mild adverse reactions. This review briefly summarizes relevant scientific data and published papers and discusses the potential mechanism and application of PDT in the treatment of oral mucosal infections.

Keywords: Drug resistance; Infection; Oral mucosa; Photodynamic therapy; Photosensitizer.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Mouth Diseases* / drug therapy
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Photosensitizing Agents