Arterial spin labeling clinical applications for brain tumors and tumor treatment complications: A comprehensive case-based review

Neuroradiol J. 2023 Apr;36(2):129-141. doi: 10.1177/19714009221114444. Epub 2022 Jul 10.

Abstract

Arterial spin labeling (ASL) is a noninvasive neuroimaging technique that allows for quantifying cerebral blood flow without intravenous contrast. Various neurovascular disorders and tumors have cerebral blood flow alterations. Identifying these perfusion changes through ASL can aid in the diagnosis, especially in entities with normal structural imaging. In addition, complications of tumor treatment and tumor progression can also be monitored using ASL. In this case-based review, we demonstrate the clinical applications of ASL in diagnosing and monitoring brain tumors and treatment complications.

Keywords: Arterial spin labeling; arterial spin labeling; glioblastoma; lymphocytic hypophysitis; meningioma; metastasis; neuroimaging; primary CNS lymphoma; radionecrosis; stroke-like migraines after radiation therapy.

Publication types

  • Review

MeSH terms

  • Brain Neoplasms* / blood supply
  • Brain Neoplasms* / diagnostic imaging
  • Brain Neoplasms* / therapy
  • Cerebrovascular Circulation
  • Humans
  • Magnetic Resonance Angiography* / methods
  • Magnetic Resonance Imaging / methods
  • Neuroimaging / methods
  • Spin Labels

Substances

  • Spin Labels