Rare Pseudosarcomatous Lesions Posing Diagnostic Challenges: Histopathologic Examination as a Dominant Tool Preventing Misdiagnosis of Proliferative Fasciitis

Cureus. 2022 Jun 8;14(6):e25770. doi: 10.7759/cureus.25770. eCollection 2022 Jun.

Abstract

Proliferative fasciitis is an extremely rare benign myofibroblastic proliferation that typically presents as a rapidly growing subcutaneous mass. Precise histopathological interpretation is required to obtain a proper diagnosis. Due to a symptomatology overlap, discrimination from soft tissue sarcomas is crucial in the prevention of unnecessary excessive treatment that could be potentially harmful to the patients. Here, we present a rare case of atypical localization of proliferative fasciitis. The lesion was predominantly localized in the groin with the invasion of the scrotum and clinically mimicked soft tissue sarcoma. However, according to a proper histopathologic analysis, the diagnosis of proliferative fasciitis was concluded. With a large number of pseudosarcomatous lesions, there is a rising urge to introduce these rare but benign processes to physicians in order to prevent misdiagnosing patients.

Keywords: marginal excision; misdiagnosis; proliferative fasciitis; pseudosarcomatous lesion; soft tissue sarcoma.

Publication types

  • Case Reports