Pre-gelled Electrode Grid for Self-Applied EEG Sleep Monitoring at Home

Carlos F da Silva Souto; Wiebke Pätzold; Marina Paul; Stefan Debener; Karen Insa Wolf

doi:10.3389/fnins.2022.883966

Pre-gelled Electrode Grid for Self-Applied EEG Sleep Monitoring at Home

Front Neurosci. 2022 Jun 24:16:883966. doi: 10.3389/fnins.2022.883966. eCollection 2022.

Authors

Carlos F da Silva Souto¹, Wiebke Pätzold¹, Marina Paul², Stefan Debener^{1

3

4}, Karen Insa Wolf¹

Affiliations

¹ Fraunhofer Institute for Digital Media Technology IDMT, Branch Hearing, Speech and Audio Technology HSA, Oldenburg, Germany.
² PSG-Auswertungs-Service, Stadtlohn, Germany.
³ Neuropsychology Laboratory, Department of Psychology, University of Oldenburg, Oldenburg, Germany.
⁴ Cluster of Excellence Hearing4All, University of Oldenburg, Oldenburg, Germany.

Abstract

The need for diagnostic capabilities for sleep disorders such as sleep apnea and insomnia far exceeds the capacity of inpatient sleep laboratories. Some home monitoring systems omit electroencephalography (EEG) because trained personnel may be needed to apply EEG sensors. Since EEG is essential for the detailed evaluation of sleep, better systems supporting the convenient and robust recording of sleep EEG at home are desirable. Recent advances in EEG acquisition with flex-printed sensors promise easier application of EEG sensor arrays for chronic recordings, yet these sensor arrays were not designed for sleep EEG. Here we explored the self-applicability of a new sleep EEG sensor array (trEEGrid) without prior training. We developed a prototype with pre-gelled neonatal ECG electrodes placed on a self-adhesive grid shape that guided the fast and correct positioning of a total of nine electrodes on the face and around the ear. Positioning of the sensors was based on the results of a previous ear-EEG sleep study (da Silva Souto et al., 2021), and included electrodes around the ear, one eye, and the chin. For comparison, EEG and electrooculogram channels placed according to the American Academy of Sleep Medicine criteria, as well as respiratory inductance plethysmography on thorax and abdomen, oxygen saturation, pulse and body position were included with a mobile polysomnography (PSG) system. Two studies with 32 individuals were conducted to compare the signal quality of the proposed flex-printed grid with PSG signals and to explore self-application of the new grid at home. Results indicate that the new array is self-applicable by healthy participants without on-site hands-on support. A comparison of the hypnogram annotations obtained from the data of both systems revealed an overall substantial agreement on a group level (Cohen's κ = 0.70 ± 0.01). These results suggest that flex-printed pre-gelled sensor arrays designed for sleep EEG acquisition can facilitate self-recording at home.

Keywords: EEG; flexible PCB electrodes; grapho-elements; self-application; sleep staging.