Clinical Implications of a Persistent Left Superior Vena Cava in a Patient With Right Superior Vena Cava Thrombosis Undergoing Emergency Deceased Donor Liver Transplantation: A Case Report

Transplant Proc. 2022 Jul-Aug;54(6):1648-1653. doi: 10.1016/j.transproceed.2022.03.052. Epub 2022 Jul 7.

Abstract

Background: Persistent left superior vena cava (PLSVC) is the most common congenital thoracic venous anomaly. It is usually found incidentally on examination or during invasive procedures. In most cases, the blood flows back to the right atrium through the coronary sinus without hemodynamic abnormalities and it is usually asymptomatic. There is some controversy regarding the clinical use of PLSVC. In a few cases, a PLSVC has been used for hemodialysis or large-bore intravenous access.

Case report: A 62-year-old woman with a previous hepatectomy for hepatocellular carcinoma and liver cirrhosis developed hepatic failure. Owing to her worsening condition, she needed liver transplantation (LT). However, a superior vena cava thrombus was found between the right atrium and proximal superior vena cava on preoperative transesophageal echocardiography. Usually, right-sided central venous catheterization is performed for LT preparation, but the embolic risk was very high in our patient. Fortunately, she had already been diagnosed with PLSVC. Therefore, we decided to perform fluoroscopy-guided catheterization through the PLSVC. For the safe use of a PLSVC catheter during surgery, the rapid infusion system pressure, coronary sinus inflow pressure, and intraoperative transesophageal echocardiography were monitored. The patient successfully underwent LT.

Conclusions: Based on a literature review and this case, PLSVC can be used clinically when accompanied by a detailed history, preoperative imaging examination, and close intraoperative monitoring. We suggest that a PLSVC is a feasible alternative to central venous access for LT.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Humans
  • Liver Transplantation* / adverse effects
  • Living Donors
  • Middle Aged
  • Persistent Left Superior Vena Cava*
  • Superior Vena Cava Syndrome* / complications
  • Thrombosis* / complications
  • Vascular Malformations* / complications
  • Vena Cava, Superior / abnormalities
  • Vena Cava, Superior / diagnostic imaging
  • Vena Cava, Superior / surgery