Recent advances on biomedical applications of pectin-containing biomaterials

Reza Eivazzadeh-Keihan; Ehsan Bahojb Noruzi; Hooman Aghamirza Moghim Aliabadi; Sahra Sheikhaleslami; Ali Reza Akbarzadeh; Seyed Masoud Hashemi; Mostafa Ghafori Gorab; Ali Maleki; Reza Ahangari Cohan; Mohammad Mahdavi; Roksana Poodat; Faeze Keyvanlou; Mir Saeed Esmaeili

doi:10.1016/j.ijbiomac.2022.07.016

Recent advances on biomedical applications of pectin-containing biomaterials

Int J Biol Macromol. 2022 Sep 30:217:1-18. doi: 10.1016/j.ijbiomac.2022.07.016. Epub 2022 Jul 6.

Affiliations

¹ Nanobiotechnology Department, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran.
² Faculty of Chemistry, Department of Inorganic Chemistry, University of Tabriz, Tabriz, Iran.
³ Protein Chemistry Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran; Advanced Chemical Studies Lab, Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran.
⁴ Advanced Chemical Studies Lab, Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran.
⁵ Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran.
⁶ Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran.
⁷ Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran. Electronic address: maleki@iust.ac.ir.
⁸ Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: momahdavi@sina.tums.ac.ir.

PMID: 35809676
DOI: 10.1016/j.ijbiomac.2022.07.016

Abstract

There is a growing demand for biomaterials developing with novel properties for biomedical applications hence, hydrogels with 3D crosslinked polymeric structures obtained from natural polymers have been deeply inspected in this field. Pectin a unique biopolymer found in the cell walls of fruits and vegetables is extensively used in the pharmaceutical, food, and textile industries due to its ability to form a thick gel-like solution. Considering biocompatibility, biodegradability, easy gelling capability, and facile manipulation of pectin-based biomaterials; they have been thoroughly investigated for various potential biomedical applications including drug delivery, wound healing, tissue engineering, creation of implantable devices, and skin-care products.

Keywords: Biosensor; Drug delivery; Hydrogel; Pectin; Tissue engineering; Wound dressing.

Publication types

Review

MeSH terms

Biocompatible Materials* / chemistry
Biocompatible Materials* / pharmacology
Drug Delivery Systems
Hydrogels / chemistry
Pectins* / chemistry
Polymers
Tissue Engineering

Substances

Biocompatible Materials
Hydrogels
Polymers
Pectins