An Evidence-Based Review of Application Devices for Nitric Oxide Concentration Determination from Exhaled Air in the Diagnosis of Inflammation and Treatment Monitoring

Molecules. 2022 Jul 3;27(13):4279. doi: 10.3390/molecules27134279.

Abstract

The measurement of nitric oxide (NO) in exhaled air is used in diagnostics and monitoring the pathologies not only in the respiratory system but also in the oral cavity. It has shown a huge increase in its level in asthma and diseases of the oral cavity. It seems reasonable to undertake research on the impact of inflammation on the level of NO in exhaled air. The aim of the study is to make an evidence-based review of the application of NO levels in exhaled air in the diagnosis of inflammation and treatment monitoring on the basis of selected measuring devices.

Methods and results: This paper presents an example of the application of NO measurement in exhaled air in individual human systems. Selected measuring devices, their non-invasiveness, and their advantages are described.

Discussion: The usefulness of this diagnostic method in pathologies of the oral cavity was noted.

Conclusions: Measuring the level of NO in exhaled air seems to be a useful diagnostic method.

Keywords: exhaled air; inflammation markers; inflammation process; nitric oxide; non-invasive diagnostics; oral cavity.

Publication types

  • Review

MeSH terms

  • Asthma* / diagnosis
  • Asthma* / therapy
  • Exhalation
  • Humans
  • Inflammation / diagnosis
  • Nitric Oxide*
  • Respiratory System

Substances

  • Nitric Oxide