A high-performance SERS imprinted membrane based on Ag/CNTs for selective detection of spiramycin

Hongji Li; Junfu Wang; Xiyue Wang; Haochen Yu; Linjing Ji; Tianyu Zhou; Chunbo Liu; Guangbo Che; Dandan Wang

doi:10.1016/j.saa.2022.121587

A high-performance SERS imprinted membrane based on Ag/CNTs for selective detection of spiramycin

Spectrochim Acta A Mol Biomol Spectrosc. 2022 Nov 15:281:121587. doi: 10.1016/j.saa.2022.121587. Epub 2022 Jul 2.

Authors

Hongji Li¹, Junfu Wang², Xiyue Wang³, Haochen Yu³, Linjing Ji³, Tianyu Zhou¹, Chunbo Liu⁴, Guangbo Che⁵, Dandan Wang⁶

Affiliations

¹ Key Laboratory of Preparation and Applications of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun 130103, PR China; College of Environmental Science and Engineering, Jilin Normal University, Siping 136000, China.
² College of Chemistry, Jilin Normal University, Siping 136000, PR China.
³ College of Environmental Science and Engineering, Jilin Normal University, Siping 136000, China.
⁴ Key Laboratory of Preparation and Applications of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun 130103, PR China; College of Environmental Science and Engineering, Jilin Normal University, Siping 136000, China. Electronic address: chunboliu@jlnu.edu.cn.
⁵ Key Laboratory of Preparation and Applications of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun 130103, PR China; College of Environmental Science and Engineering, Jilin Normal University, Siping 136000, China; College of Chemistry, Baicheng Normal University, Baicheng 137018, PR China.
⁶ Key Laboratory of Preparation and Applications of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun 130103, PR China; College of Environmental Science and Engineering, Jilin Normal University, Siping 136000, China. Electronic address: dandanwang@jlnu.edu.cn.

PMID: 35797948
DOI: 10.1016/j.saa.2022.121587

Abstract

In this test, the eggshell membrane (ESM) is selected as the support membrane for the biocompatibility and anchors CNTs on the surface to increase the mechanical properties. Then Ag NPs are decorated on CNTs-ESM substrate as SERS substrate by twice in-situ reduction. Finally, a layer of imprinted polymers is coated on the surface of the substrate to synthesize the imprinted membrane for selective detection of spiramycin. It is exhibited from the characteristic results that the CNTs significantly increase the mechanical properties and the detection sensitivity, simultaneously. When the concentration of SP changes between 10^-6 ∼ 10^-11 M, there is a linear relationship between SERS intensity and SP concentration. The detection limit is 10^-11 M, and the correlation coefficient R² is 0.9864. The SERS imprinted membrane can be applied into the detection of antibiotics in practical sample, which broadens the research field of antibiotics detection.

Keywords: Antibiotic detection; Eggshell membrane; Molecularly imprinted polymers; Selective detection; Surface-enhanced Raman scattering.

MeSH terms

Anti-Bacterial Agents
Molecular Imprinting* / methods
Polymers / chemistry
Spectrum Analysis, Raman / methods
Spiramycin*

Substances

Anti-Bacterial Agents
Polymers
Spiramycin