Biomedical Microscopic Imaging in Computational Intelligence Using Deep Learning Ensemble Convolution Learning-Based Feature Extraction and Classification

Comput Intell Neurosci. 2022 Jun 27:2022:3531308. doi: 10.1155/2022/3531308. eCollection 2022.

Abstract

Microscopy image analysis gives quantitative support for enhancing the characterizations of various diseases, including breast cancer, lung cancer, and brain tumors. As a result, it is crucial in computer-assisted diagnosis and prognosis. Understanding the biological principles underlying these dynamic image sequences often necessitates precise analysis and statistical quantification, a major discipline issue. Deep learning methods are increasingly used in bioimage processing as they grow rapidly. This research proposes novel biomedical microscopic image analysis techniques using deep learning architectures based on feature extraction and classification. Here, the input image has been taken as microscopic image, and it has been processed and analyzed for noise removal, edge smoothening, and normalization. The processed image has been extracted based on their features in microscopic image analysis using ConVol_NN architecture with AlexNet model. Then, the features have been classified using ensemble of Inception-ResNet and VGG-16 (EN_InResNet_VGG-16) architectures. The experimental results show various dataset analyses in terms of accuracy of 98%, precision of 90%, computational time of 79%, SNR of 89%, and MSE of 62%.

MeSH terms

  • Deep Learning*
  • Diagnosis, Computer-Assisted
  • Diagnostic Imaging
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Neural Networks, Computer