The COVID-19 continues to spread throughout the world, and local clusters and outbreaks related to overseas imports have occurred in many places in China. Vaccination against COVID-19 is one of the most effective tools to prevent disease, severe illness and death. For vaccines developed and used by China, it is particularly important for scientific and targeted prevention and control to study different outbreak scenarios, to conduct in-depth real-world research on SARS-CoV-2 variants, and to further promote vaccine development and technical reserves. This article commented the effectiveness of COVID-19 vaccine, and prospected the future research on vaccine efficacy, immunization strategy and vaccine development, which provided evidence for optimizing vaccination strategy.
新型冠状病毒肺炎疫情在全球范围持续蔓延，我国多地出现与输入病例关联的本土疫情。接种新型冠状病毒疫苗是预防新型冠状病毒发病、重症及死亡的最有效方法之一。针对我国研发和使用的疫苗种类，利用不同的疫情暴发现场对各类变异株进行深入的真实世界研究，并进一步推进针对变异株的疫苗研发和技术储备，对科学精准防控尤为重要。本文探讨了新型冠状病毒病毒疫苗效果，并对未来的疫苗效果评价研究、免疫策略研究及疫苗研发进行了展望，为优化疫苗接种策略提供依据。.