Advances in nanosensors for cardiovascular disease detection

Abstract

Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality around the world. The physiological or pathological processes of CVDs can be well indicated by timely and accurate diagnosis of relevant biomarkers and function parameters. Nanosensors integrating the advantages of nanomaterials and sensing platforms have shown good potential for rapid diagnosis of CVDs, especially for early prediction. In this review, recent advances in nanosensors for the detection of CVDs are summarized, including electrochemical, optical, pressure, and paper-based nanosensors. Design strategies for different nanosensors and the corresponding sensing nanomaterials, mechanisms, and properties are briefly discussed. This review also offered a preliminary analysis of the obstacles and prospects for using nanosensors to diagnose CVDs.

Keywords: Biomarkers; Cardiovascular diseases (CVDs); Early diagnosis; Nanomaterials; Nanosensors.