Optic Neuropathy following Botulinum Toxin Injection into the Medial Rectus Muscle for Diplopia

Mohammad Reza Khalili; Shahla Hosseini; Mohammad Shirvani; Maryam Sadat Sadati

doi:10.18502/jovr.v17i2.10806

Optic Neuropathy following Botulinum Toxin Injection into the Medial Rectus Muscle for Diplopia

J Ophthalmic Vis Res. 2022 Apr 29;17(2):296-302. doi: 10.18502/jovr.v17i2.10806. eCollection 2022 Apr-Jun.

Authors

Mohammad Reza Khalili¹, Shahla Hosseini¹, Mohammad Shirvani¹, Maryam Sadat Sadati²

Affiliations

¹ Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
² Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

Purpose: To report a case of optic neuropathy (ON) following botulinum toxin A (BTA) injection into the medial rectus muscle.

Case report: We describe a 37-year-old man with unilateral ON after a BTA injection into the left medial rectus for treatment of traumatic sixth nerve palsy. Oral prednisolone was prescribed for 14 days. After two weeks, his visual acuity returned to 20/20.

Conclusion: Botulinum toxin-induced neuropathy is a rare and vision-threatening complication of BTA. In patients with recent injection of BTA who present with visual complaints, botulinum toxin-induced neuropathy should be considered.

Keywords: Diplopia; Optic Neuropathy; Botulinum Toxin.

Publication types

Case Reports