COVID-19 clusters in a teaching hospital during the second wave of the SARS-CoV-2 pandemic in France: A descriptive study and lessons learned for waves to come

Cédric Dananché; Christelle Elias; Nicolas Guibert; Sophie Gardes; Christine Barreto; Marie-Agnès Denis; Pascal Fascia; Solweig Gerbier; Béatrice Grisi; Nagham Khanafer; Amélie Massardier-Pilonchéry; Élodie Munier-Marion; Claudine Pasquet; Jean-Baptiste Fassier; Philippe Vanhems

doi:10.1016/j.ajic.2022.06.018

COVID-19 clusters in a teaching hospital during the second wave of the SARS-CoV-2 pandemic in France: A descriptive study and lessons learned for waves to come

Am J Infect Control. 2022 Sep;50(9):1060-1063. doi: 10.1016/j.ajic.2022.06.018. Epub 2022 Jun 26.

Authors

Affiliations

¹ Hospices Civils de Lyon, Service Hygiène, Épidémiologie, Infectiovigilance et Prévention, Lyon, France; CIRI, Centre International de Recherche en Infectiologie, (Team Public Health, Epidemiology and Evolutionnary Ecology of Infectious Diseases (PHE3ID)), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. Electronic address: cedric.dananche@chu-lyon.fr.
² Hospices Civils de Lyon, Service Hygiène, Épidémiologie, Infectiovigilance et Prévention, Lyon, France; CIRI, Centre International de Recherche en Infectiologie, (Team Public Health, Epidemiology and Evolutionnary Ecology of Infectious Diseases (PHE3ID)), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.
³ Hospices Civils de Lyon, Service de Médecine du Travail, Lyon, France; Unité Mixte de Recherche Épidémiologique et de Surveillance Transport Travail Environnement, UMRESTTE, UMR 9405 (Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux, IFSTTAR; Université Eiffel; Université Lyon 1), Bron, France.
⁴ Hospices Civils de Lyon, Service Hygiène, Épidémiologie, Infectiovigilance et Prévention, Lyon, France.
⁵ Hospices Civils de Lyon, Service de Médecine du Travail, Lyon, France.
⁶ Hospices Civils de Lyon, Service Hygiène, Épidémiologie, Infectiovigilance et Prévention, Lyon, France; CIRI, Centre International de Recherche en Infectiologie, (Team Public Health, Epidemiology and Evolutionnary Ecology of Infectious Diseases (PHE3ID)), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. Electronic address: philippe.vanhems@chu-lyon.fr.

Abstract

A total of 92 coronavirus disease 2019 clusters involving 1,156 individuals (729 patients and 427 healthcare workers) occurred in Lyon University Hospital between September 1, 2020 and March 31, 2021, mostly on medical and geriatric wards. The number of clusters was closely correlated to the trend in coronavirus disease 2019 community incidence over time; in-hospital clusters did not persist when community incidence decreased. Recommended preventive measures were not fully applicable due to specific ward-associated determinants and patient characteristics.

Keywords: COVID-19; Cluster; Community incidence; Healthcare-associated infection; SARS-CoV-2.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
COVID-19* / epidemiology
Health Personnel
Hospitals, Teaching
Humans
Pandemics* / prevention & control
SARS-CoV-2