Application of Graphene Oxide-Based Hydrogels in Bone Tissue Engineering

ACS Biomater Sci Eng. 2022 Jul 11;8(7):2849-2857. doi: 10.1021/acsbiomaterials.2c00396. Epub 2022 Jun 27.

Abstract

As an important derivative of graphene-based materials, graphene oxide (GO) not only plays an important role not only in optoelectronics and sensing but also in biology due to its unique mechanical, electronic, and optical properties. This article reviews the application of GO-based hydrogels in bone tissue engineering. Whether it is a hydrogel synthesized with natural polymer compounds, synthetic polymer chemicals, bioceramics, bioactive factors, or other materials, the addition of GO can significantly improve various properties of the hydrogel. We also introduce some high-performance GO-based hydrogels in this paper, proposing some insights into materials that may be applied to bone tissue engineering in the future.

Keywords: bone tissue engineering; graphene oxide; hydrogel; scaffold.

Publication types

  • Review

MeSH terms

  • Graphite*
  • Hydrogels* / chemistry
  • Polymers
  • Tissue Engineering

Substances

  • Hydrogels
  • Polymers
  • graphene oxide
  • Graphite