Effects of resistance training on the glycemic control of people with type 1 diabetes: a systematic review and meta-analysis

Arch Endocrinol Metab. 2022;66(4):533-540. doi: 10.20945/2359-3997000000487. Epub 2022 Jun 23.

Abstract

Resistance training has shown the potential to contribute to better glycemic control in people with Type 1 Diabetes (T1D), however, there are contradictory results in this regard and a need to clarify the effects of isolated resistance training on glycemic control in T1D. The aim was to verify the effects of resistance training on the glycemic control of people with T1D. Original articles were selected, randomized and non-randomized clinical trials that aimed to verify chronic responses, through the concentrations of glycated hemoglobin (HbA1c), to a structured program of resistance exercise in the glycemia of patients with T1D. The following databases were searched; MEDLINE, PubMed, Web of Science, Scopus, ScienceDirect, LILACS, and SciELO. Five studies were included in the review. A reduction in HbA1c was observed (SMD = -0.568 ± 0.165 [95% CI = -0.891 to -0.246]; p = 0.001; I2 = 82%) in patients undergoing resistance training, when compared to the control group (SMD = 1.006 ± 0.181 [95% CI = 0.653 to 1.360]; p <0.001). Two studies, with children and adolescents and longer interventions, demonstrated a significant reduction in HbA1c, increased strength, and an improved lipid profile. Resistance training was efficient for assisting in glycemic control in people with T1D and should be incorporated in treatment plans.

Keywords: Chronic disease; metabolism; physical activity.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Adolescent
  • Blood Glucose
  • Child
  • Diabetes Mellitus, Type 1* / therapy
  • Glycated Hemoglobin / analysis
  • Glycemic Control
  • Humans
  • Resistance Training* / methods

Substances

  • Blood Glucose
  • Glycated Hemoglobin A

Grants and funding

Funding: this research was funded by a grant from the National Council for Scientific and Technological Development (CNPq) (grant number: 487557/2013-1). And Coordination for the Improvement of Higher Education Personnel (Capes) with provision of scholarships.