Recurrent Painful Ophthalmoplegic Neuropathy in an Adult Patient: A Case Report With Literature Review

Cureus. 2022 May 24;14(5):e25297. doi: 10.7759/cureus.25297. eCollection 2022 May.

Abstract

Recurrent painful ophthalmoplegic neuropathy (RPON), previously known as ophthalmoplegic migraine, is a rare disease that predominantly affects children. Recurrent episodes of ocular cranial nerve paresis with ipsilateral headache characterize this disorder. Diagnosis is mainly clinical with imaging being used as an adjunct. The pathophysiology of the disease is unknown. We present here a case of RPON in a 50-year-old female presenting with multiple episodes of headache and diplopia with associated transient thickening and enhancement of the ipsilateral oculomotor nerve on magnetic resonance imaging (MRI).

Keywords: cranial nerve enhancement; diplopia; ophthalmoplegic migraine; recurrent painful ophthalmoplegic neuropathy; third nerve palsy.

Publication types

  • Case Reports