Safety Criteria for Solid-Liquid Heterogeneous Systems in Semibatch Reactors

Zheng Ran; Lei Ni; Yong Pan; Yutong Chen; Jun Wang; Juncheng Jiang; Chi-Min Shu

doi:10.1021/acsomega.2c02139

Safety Criteria for Solid-Liquid Heterogeneous Systems in Semibatch Reactors

ACS Omega. 2022 Jun 8;7(24):21207-21219. doi: 10.1021/acsomega.2c02139. eCollection 2022 Jun 21.

Authors

Zheng Ran¹, Lei Ni¹, Yong Pan¹, Yutong Chen¹, Jun Wang¹, Juncheng Jiang^{1

2}, Chi-Min Shu³

Affiliations

¹ College of Safety Science and Engineering, Nanjing Tech University, Nanjing, Jiangsu 211816, China.
² School of Environment and Safety Engineering, Changzhou University, Changzhou, Jiangsu 213164, China.
³ Department of Safety, Health, and Environmental Engineering, National Yunlin University of Science and Technology, Yunlin 64002, Taiwan, ROC.

Abstract

An exothermic reaction in a semibatch reactor can potentially cause thermal runaway due to evolved energy accumulation or a secondary reaction. This research aims to propose safety criteria for solid-liquid reactions in semibatch reactors. Simulation modeling was carried out to build thermal runaway criteria for solid-liquid reactions in semibatch reactors. A new model for the energy and mass balance of solid-liquid reactions was successfully established. Criteria for the safety boundary diagram and the temperature diagram were ameliorated for solid-liquid reactions. The results showed that the dissolution heat has a great influence on the thermal behavior of the reaction. Experiments to neutralize citric acid and sodium hydroxide were carried out to determine the critical parameters for the neutralization reaction using the temperature diagram criterion. The proposed criteria would be reasonably expected to provide some guidance for chemical process optimization and safety design for engineering.